Endocrine Abstracts

Background: Neuroendocrine neoplasms (NEN) are known to be associated with specific familial syndromes. However, the incidence of pathogenic germline variants (PGVs) in unselected NEN patients is unknown. In this study, we aim to determine the prevalence and clinical utility of PGVs in unselected NEN patients using universal a genetic testing approach.Methods: We undertook a prospective study of germline genetic testing using a > 80 gene next-generat...